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Target5-hydroxytryptamine receptor 6
LigandBDBM50334265
Substrate/Competitorn/a
Meas. Tech.ChEMBL_699426 (CHEMBL1647453)
Ki 63.5±n/a nM
Citation Nirogi, RVDeshpande, ADKambhampati, RBadange, RKKota, LDaulatabad, AVShinde, AKAhmad, IKandikere, VJayarajan, PDubey, PK Indole-3-piperazinyl derivatives: novel chemical class of 5-HT(6) receptor antagonists. Bioorg Med Chem Lett21:346-9 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 6
Name:5-hydroxytryptamine receptor 6
Synonyms:5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:46968.43
Organism:Homo sapiens (Human)
Description:P50406
Residue:440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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  Blast E-value cutoff:
BDBM50334265
n/a
NameBDBM50334265
Synonyms:6-Chloro-1-(2,5-dimethoxybenzenesulfonyl)-3-(4-ethylpiperazin-1-yl)-1H-indole | CHEMBL1642429
TypeSmall organic molecule
Emp. Form.C22H26ClN3O4S
Mol. Mass.463.978
SMILESCCN1CCN(CC1)c1cn(c2cc(Cl)ccc12)S(=O)(=O)c1cc(OC)ccc1OC
Structure
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