| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50334583 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_698537 (CHEMBL1647712) |
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| EC50 | 6.5±n/a nM |
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| Citation |  El Bakali, J; Muccioli, GG; Renault, N; Pradal, D; Body-Malapel, M; Djouina, M; Hamtiaux, L; Andrzejak, V; Desreumaux, P; Chavatte, P; Lambert, DM; Millet, R 4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands: structural insights into the design of a novel inverse agonist series. J Med Chem53:7918-31 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50334583 |
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| n/a |
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| Name | BDBM50334583 |
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| Synonyms: | (R,S)-N3-(1-(1-Adamantyl)ethyl)-4-oxo-1-pentyl-6-phenyl-1,4-dihydropyridine-3-carboxamide | CHEMBL1641940 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H38N2O2 |
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| Mol. Mass. | 446.6242 |
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| SMILES | CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:11:13:16.15.20:18,THB:14:15:18:22.13.21,14:13:16.15.20:18,11:13:16:20.19.18,21:13:16:20.19.18,21:19:16:22.14.13| |
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| Structure | 
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