| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50334588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_698535 (CHEMBL1647710) |
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| Ki | >3000±n/a nM |
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| Citation |  El Bakali, J; Muccioli, GG; Renault, N; Pradal, D; Body-Malapel, M; Djouina, M; Hamtiaux, L; Andrzejak, V; Desreumaux, P; Chavatte, P; Lambert, DM; Millet, R 4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands: structural insights into the design of a novel inverse agonist series. J Med Chem53:7918-31 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50334588 |
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| n/a |
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| Name | BDBM50334588 |
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| Synonyms: | (R,S)-N3-(1-(1-Adamantyl)ethyl)-1,6-diphenyl-4-oxo-1,4-dihydropyridine-3-carboxamide | CHEMBL1641941 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H32N2O2 |
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| Mol. Mass. | 452.5873 |
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| SMILES | CC(NC(=O)c1cn(-c2ccccc2)c(cc1=O)-c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:1:24:27.26.31:29,THB:25:26:29:33.24.32,25:24:27.26.31:29,1:24:27:31.30.29,32:24:27:31.30.29,32:30:27:33.25.24| |
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| Structure | 
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