| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50157654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_715069 (CHEMBL1664119) |
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| Ki | 8.87±n/a nM |
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| Citation |  Yaziji, V; Rodríguez, D; Gutiérrez-de-Terán, H; Coelho, A; Caamaño, O; García-Mera, X; Brea, J; Loza, MI; Cadavid, MI; Sotelo, E Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem54:457-71 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50157654 |
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| n/a |
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| Name | BDBM50157654 |
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| Synonyms: | CHEMBL376778 | LUF-5737 | N-(4,6-diphenylpyrimidin-2-yl)isobutyramide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19N3O |
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| Mol. Mass. | 317.3844 |
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| SMILES | CC(C)C(=O)Nc1nc(cc(n1)-c1ccccc1)-c1ccccc1 |
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| Structure | 
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