| Reaction Details |
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 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 1 |
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| Ligand | BDBM24813 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_716830 (CHEMBL1670752) |
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| Ki | 12000±n/a nM |
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| Citation |  Dolušic, E; Larrieu, P; Blanc, S; Sapunaric, F; Norberg, B; Moineaux, L; Colette, D; Stroobant, V; Pilotte, L; Colau, D; Ferain, T; Fraser, G; Galleni, M; Galeni, M; Frère, JM; Masereel, B; Van den Eynde, B; Wouters, J; Frédérick, R Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. Bioorg Med Chem19:1550-61 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Indoleamine 2,3-dioxygenase 1 |
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| Name: | Indoleamine 2,3-dioxygenase 1 |
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| Synonyms: | I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase |
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| Type: | Enzyme |
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| Mol. Mass.: | 45330.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14902 |
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| Residue: | 403 |
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| Sequence: | MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
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| BDBM24813 |
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| n/a |
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| Name | BDBM24813 |
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| Synonyms: | Brassinin, 1 | N-(1H-indol-3-ylmethyl)(methylsulfanyl)carbothioamide | methyl N-(1H-indol-3-ylmethyl)carbamodithioate |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12N2S2 |
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| Mol. Mass. | 236.356 |
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| SMILES | CSC(=S)NCc1c[nH]c2ccccc12 |
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| Structure | 
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