| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin L2 |
|---|
| Ligand | BDBM50336480 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_716901 (CHEMBL1670880) |
|---|
| Ki | 4200±n/a nM |
|---|
| Citation |  Severino, RP; Guido, RV; Marques, EF; Brömme, D; da Silva, MF; Fernandes, JB; Andricopulo, AD; Vieira, PC Acridone alkaloids as potent inhibitors of cathepsin V. Bioorg Med Chem19:1477-81 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin L2 |
|---|
| Name: | Cathepsin L2 |
|---|
| Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37341.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O60911 |
|---|
| Residue: | 334 |
|---|
| Sequence: | MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
|
|
|
|---|
| BDBM50336480 |
|---|
| n/a |
|---|
| Name | BDBM50336480 |
|---|
| Synonyms: | 1,3,5-trihydroxy-4-methoxy-10-methylacridone | CHEMBL465847 | citrusinine-II |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13NO5 |
|---|
| Mol. Mass. | 287.2674 |
|---|
| SMILES | COc1c(O)cc(O)c2c1n(C)c1c(O)cccc1c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
