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TargetDelta-type opioid receptor
LigandBDBM50336612
Substrate/Competitorn/a
Meas. Tech.ChEMBL_725831
Ki 547±n/a nM
Citation Cheng KLee YSRothman RBDersch CMBittman RWJacobson AERice KC Probes for narcotic receptor mediated phenomena. 41. Unusual inverseµ-agonists and potentµ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans. J Med Chem 54:957-69 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Opioid receptors; mu/kappa/delta
Synonyms:D-OR-1 | DOR-1 | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50336612
n/a
NameBDBM50336612
Synonyms:3-((1S,5R)-2-(((1'S,2'R)-2-Phenylcyclopropyl)methyl)-2-azabicyclo[3.3.1]nonan-5-yl)phenol hydrochloride | CHEMBL1672187
TypeSmall organic molecule
Emp. Form.C24H29NO
Mol. Mass.347.4932
SMILESOc1cccc(c1)[C@]12CCC[C@H](C1)N(C[C@H]1C[C@H]1c1ccccc1)CC2 |r|
Structure
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