| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM50337592 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_728639 (CHEMBL1685769) |
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| EC50 | >10000±n/a nM |
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| Citation |  Kurata, H; Otsuki, K; Kusumi, K; Kurono, M; Terakado, M; Seko, T; Mizuno, H; Ono, T; Hagiya, H; Minami, M; Nakade, S; Habashita, H Structure-activity relationship studies of sphingosine-1-phosphate receptor agonists with N-cinnamyl-ß-alanine moiety. Bioorg Med Chem Lett21:1390-3 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38883.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
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| Residue: | 353 |
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| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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| BDBM50337592 |
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| n/a |
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| Name | BDBM50337592 |
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| Synonyms: | 3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)propanoic acid | CHEMBL1683041 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31NO3 |
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| Mol. Mass. | 369.4971 |
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| SMILES | OC(=O)CCNCCCc1ccc(OCCCCCc2ccccc2)cc1 |
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| Structure | 
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