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TargetEnoyl-ACP reductase
LigandBDBM50338300
Substrate/Competitorn/a
Meas. Tech.ChEMBL_728028
IC50 6000±n/a nM
Citation Cho JYKwon YJSohn MJSeok SJKim WG Phellinstatin, a new inhibitor of enoyl-ACP reductase produced by the medicinal fungus Phellinus linteus. Bioorg Med Chem Lett 21:1716-8 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-ACP reductase
Name:Enoyl-ACP reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:26446.66
Organism:Staphylococcus aureus
Description:ChEMBL_1455655
Residue:243
Sequence:
YVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQ
SDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIV
AHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAI
SAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHV
DSG
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BDBM50338300
n/a
NameBDBM50338300
Synonyms:CHEMBL1682259 | phellinstatin
TypeSmall organic molecule
Emp. Form.C39H26O15
Mol. Mass.734.6147
SMILESOc1cc(oc(=O)c1)[C@@H]1[C@H](Oc2cc(\C=C\c3cc(O)c(O)cc3-c3c(O)cc(\C=C\c4ccc(O)c(O)c4)oc3=O)oc(=O)c12)c1ccc(O)c(O)c1 |r,wU:8.8,wD:9.51,(-3.09,.5,;-1.55,.47,;-.81,-.89,;.72,-.91,;1.53,.41,;.78,1.75,;1.59,3.07,;-.76,1.79,;1.47,-2.26,;.55,-3.5,;1.46,-4.75,;2.92,-4.29,;4.25,-5.07,;5.59,-4.3,;6.92,-5.07,;8.25,-4.3,;9.58,-5.06,;10.92,-4.3,;12.25,-5.06,;13.59,-4.29,;12.26,-6.61,;13.59,-7.38,;10.92,-7.38,;9.58,-6.61,;7.48,-7.73,;6.17,-6.92,;6.11,-5.65,;4.82,-7.66,;4.79,-9.21,;3.44,-9.95,;2.12,-9.15,;.77,-9.89,;-.54,-9.09,;-1.88,-9.83,;-1.92,-11.37,;-3.27,-12.11,;-.59,-12.17,;-.62,-13.71,;.75,-11.42,;6.12,-10.01,;7.46,-9.26,;8.78,-10.06,;5.59,-2.75,;4.26,-1.98,;4.26,-.44,;2.93,-2.74,;-.98,-3.49,;-1.76,-4.81,;-3.3,-4.81,;-4.06,-3.47,;-5.61,-3.45,;-3.28,-2.14,;-4.04,-.79,;-1.74,-2.15,)|
Structure
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