| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50339465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_736594 (CHEMBL1692323) |
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| EC50 | 47±n/a nM |
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| Citation |  Sasaki, S; Kitamura, S; Negoro, N; Suzuki, M; Tsujihata, Y; Suzuki, N; Santou, T; Kanzaki, N; Harada, M; Tanaka, Y; Kobayashi, M; Tada, N; Funami, M; Tanaka, T; Yamamoto, Y; Fukatsu, K; Yasuma, T; Momose, Y Design, synthesis, and biological activity of potent and orally available G protein-coupled receptor 40 agonists. J Med Chem54:1365-78 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM50339465 |
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| n/a |
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| Name | BDBM50339465 |
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| Synonyms: | 3-(4-{[3-(2,6-Dimethylphenoxy)benzyl]oxy}phenyl)propanoic Acid | CHEMBL1688462 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24O4 |
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| Mol. Mass. | 376.445 |
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| SMILES | Cc1cccc(C)c1Oc1cccc(COc2ccc(CCC(O)=O)cc2)c1 |
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| Structure | 
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