| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM50339588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_736725 (CHEMBL1695106) |
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| Ki | 1120±n/a nM |
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| Citation |  Davis, RA; Hofmann, A; Osman, A; Hall, RA; Mühlschlegel, FA; Vullo, D; Innocenti, A; Supuran, CT; Poulsen, SA Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases. J Med Chem54:1682-92 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | Carbonic Anhydrase 2 (Can2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 26594.37 |
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| Organism: | Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii) |
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| Description: | n/a |
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| Residue: | 239 |
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| Sequence: | MPFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQA
PNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVM
VVGHTGCGGCIAAFDQPLPTEENPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMA
VKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHPFVDDRVPRA
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| BDBM50339588 |
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| n/a |
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| Name | BDBM50339588 |
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| Synonyms: | (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID | 2-(3-chloro-4-hydroxyphenyl)acetic acid | 3-chloro-4-hydroxyphenylacetic acid | CHEMBL592010 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7ClO3 |
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| Mol. Mass. | 186.592 |
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| SMILES | OC(=O)Cc1ccc(O)c(Cl)c1 |
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| Structure | 
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