| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase |
|---|
| Ligand | BDBM50339592 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_736725 (CHEMBL1695106) |
|---|
| Ki | 890±n/a nM |
|---|
| Citation |  Davis, RA; Hofmann, A; Osman, A; Hall, RA; Mühlschlegel, FA; Vullo, D; Innocenti, A; Supuran, CT; Poulsen, SA Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases. J Med Chem54:1682-92 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase |
|---|
| Name: | Carbonic anhydrase |
|---|
| Synonyms: | Carbonic Anhydrase 2 (Can2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26594.37 |
|---|
| Organism: | Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii) |
|---|
| Description: | n/a |
|---|
| Residue: | 239 |
|---|
| Sequence: | MPFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQA
PNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVM
VVGHTGCGGCIAAFDQPLPTEENPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMA
VKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHPFVDDRVPRA
|
|
|
|---|
| BDBM50339592 |
|---|
| n/a |
|---|
| Name | BDBM50339592 |
|---|
| Synonyms: | 2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imidazol-5(4H)-one | CHEMBL603189 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H11N3O3 |
|---|
| Mol. Mass. | 233.2233 |
|---|
| SMILES | COc1cc(C=C2N=C(N)NC2=O)ccc1O |w:5.4,t:7| |
|---|
| Structure | 
|
|---|
Search and Browse
