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TargetCarbonic Anhydrase 2 (Can2)
LigandBDBM50339593
Substrate/Competitorn/a
Meas. Tech.ChEMBL_736725
Ki 950±n/a nM
Citation Davis RAHofmann AOsman AHall RAMühlschlegel FAVullo DInnocenti ASupuran CTPoulsen SA Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases. J Med Chem 54:1682-92 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic Anhydrase 2 (Can2)
Name:Carbonic Anhydrase 2 (Can2)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:26594.37
Organism:Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii)
Description:n/a
Residue:239
Sequence:
MPFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQA
PNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVM
VVGHTGCGGCIAAFDQPLPTEENPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMA
VKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHPFVDDRVPRA
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  Blast E-value cutoff:
BDBM50339593
n/a
NameBDBM50339593
Synonyms:2-amino-4-(3,4-dihydroxybenzylidene)-1H-imidazol-5(4H)-one | CHEMBL591736 | polyandrocarpamine B
TypeSmall organic molecule
Emp. Form.C10H9N3O3
Mol. Mass.219.1968
SMILESNC1=NC(=Cc2ccc(O)c(O)c2)C(=O)N1 |w:4.4,t:1|
Structure
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