| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 2 |
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| Ligand | BDBM50339638 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_735000 (CHEMBL1693607) |
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| IC50 | >10000±n/a nM |
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| Citation |  Laborde, E; Macsata, RW; Meng, F; Peterson, BT; Robinson, L; Schow, SR; Simon, RJ; Xu, H; Baba, K; Inagaki, H; Ishiwata, Y; Jomori, T; Matsumoto, Y; Miyachi, A; Nakamura, T; Okamoto, M; Handel, TM; Bernard, CC Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function. J Med Chem54:1667-81 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 2 |
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| Name: | C-C chemokine receptor type 2 |
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| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41932.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41597 |
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| Residue: | 374 |
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| Sequence: | MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN
MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY
HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK
CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR
AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI
NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI
GRAPEASLQDKEGA
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| BDBM50339638 |
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| n/a |
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| Name | BDBM50339638 |
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| Synonyms: | 5-(Benzo[d][1,3]dioxol-5-yl)-N-(3,4-dichlorophenyl)-1,2,4-oxadiazol-3-amine | CHEMBL1688886 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9Cl2N3O3 |
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| Mol. Mass. | 350.156 |
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| SMILES | Clc1ccc(Nc2noc(n2)-c2ccc3OCOc3c2)cc1Cl |
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| Structure | 
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