| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50339864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_740684 (CHEMBL1763746) |
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| Ki | 8730±n/a nM |
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| Citation |  Xia, Y; Cao, K; Zhou, Y; Alley, MR; Rock, F; Mohan, M; Meewan, M; Baker, SJ; Lux, S; Ding, CZ; Jia, G; Kully, M; Plattner, JJ Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors. Bioorg Med Chem Lett21:2533-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ENTCL | ampC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41306.67 |
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| Organism: | Enterobacter cloacae |
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| Description: | ChEMBL_40258 |
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| Residue: | 381 |
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| Sequence: | MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHY
YTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQ
WQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGA
LAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQA
YGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEA
NTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLA
NTSYPNPARVEAAYHILEALQ
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| BDBM50339864 |
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| n/a |
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| Name | BDBM50339864 |
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| Synonyms: | 6-(4-aminophenoxy)benzo[c][1,2]oxaborol-1(3H)-ol | CHEMBL1761270 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12BNO3 |
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| Mol. Mass. | 241.05 |
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| SMILES | Nc1ccc(Oc2ccc3COB(O)c3c2)cc1 |
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| Structure | 
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