| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
|---|
| Ligand | BDBM50339885 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_740704 (CHEMBL1763766) |
|---|
| IC50 | 11±n/a nM |
|---|
| Citation |  Gustin, DJ; Ma, Z; Min, X; Li, Y; Hedberg, C; Guimaraes, C; Porter, AC; Lindstrom, M; Lester-Zeiner, D; Xu, G; Carlson, TJ; Xiao, S; Meleza, C; Connors, R; Wang, Z; Kayser, F Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors. Bioorg Med Chem Lett21:2492-6 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fatty-acid amide hydrolase 1 |
|---|
| Name: | Fatty-acid amide hydrolase 1 |
|---|
| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 63071.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O00519 |
|---|
| Residue: | 579 |
|---|
| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
|
|
|
|---|
| BDBM50339885 |
|---|
| n/a |
|---|
| Name | BDBM50339885 |
|---|
| Synonyms: | 3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-1-ethyl-2-methyl-1H-pyrrolo[2,3-b]pyridine | CHEMBL1761308 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H27N5S |
|---|
| Mol. Mass. | 453.602 |
|---|
| SMILES | CCn1c(C)c(C2CCCN(C2)c2nccc(n2)-c2cc3ccccc3s2)c2cccnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
