| Reaction Details |
|---|
 | Report a problem with these data |
| Target | L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase |
|---|
| Ligand | BDBM50339905 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_740790 (CHEMBL1763891) |
|---|
| IC50 | 50±n/a nM |
|---|
| Citation |  Gutierrez-Lugo, MT; Bewley, CA Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors. Bioorg Med Chem Lett21:2480-3 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase |
|---|
| Name: | L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase |
|---|
| Synonyms: | L-Cys:GlcN-Ins ligase | MSH ligase | MSHC_MYCTU | Mycothiol ligase | cysS2 | mshC |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45583.42 |
|---|
| Organism: | Mycobacterium tuberculosis |
|---|
| Description: | ChEMBL_754210 |
|---|
| Residue: | 414 |
|---|
| Sequence: | MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV
TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV
LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR
DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR
IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV
LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV
VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL
|
|
|
|---|
| BDBM50339905 |
|---|
| n/a |
|---|
| Name | BDBM50339905 |
|---|
| Synonyms: | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE | 5'-O-[N-(L-cysteinyl)sulfamoyl]adenosine | CHEMBL1163074 | CysSA |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H19N7O7S2 |
|---|
| Mol. Mass. | 449.463 |
|---|
| SMILES | N[C@@H](CS)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
