| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50340326 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_741504 (CHEMBL1763819) |
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| Ki | 16±n/a nM |
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| Citation |  Jeanty, M; Suzenet, F; Delagrange, P; Nosjean, O; Boutin, JA; Caignard, DH; Guillaumet, G Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists. Bioorg Med Chem Lett21:2316-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50340326 |
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| n/a |
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| Name | BDBM50340326 |
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| Synonyms: | CHEMBL1760956 | N-(2-(3-iodo-6-methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl)acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14IN3O2 |
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| Mol. Mass. | 359.1629 |
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| SMILES | COc1ccc2c(I)cn(CCNC(C)=O)c2n1 |
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| Structure | 
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