| Reaction Details |
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 | Report a problem with these data |
| Target | Mas-related G-protein coupled receptor member X1 |
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| Ligand | BDBM50340751 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_740644 (CHEMBL1763646) |
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| IC50 | 108±n/a nM |
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| Citation |  Bayrakdarian, M; Butterworth, J; Hu, YJ; Santhakumar, V; Tomaszewski, MJ Development of 2,4-diaminopyrimidine derivatives as novel SNSR4 antagonists. Bioorg Med Chem Lett21:2102-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mas-related G-protein coupled receptor member X1 |
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| Name: | Mas-related G-protein coupled receptor member X1 |
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| Synonyms: | MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36253.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_516621 |
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| Residue: | 322 |
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| Sequence: | MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNA
FSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTER
CLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFIT
VAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFL
WIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASE
VDEGGGQLPEEILELSGSRLEQ
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| BDBM50340751 |
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| n/a |
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| Name | BDBM50340751 |
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| Synonyms: | CHEMBL1762705 | N-((3-bromopyridin-4-yl)methyl)-2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)piperazin-1-yl)-N-ethylacetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31BrClN7O |
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| Mol. Mass. | 572.928 |
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| SMILES | CCN(Cc1ccncc1Br)C(=O)CN1CCN(CC1)c1ccnc(NCCc2ccc(Cl)cc2)n1 |
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| Structure | 
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