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TargetOligopeptide transporter small intestine isoform
LigandBDBM50341599
Substrate/Competitorn/a
Meas. Tech.ChEMBL_744113
IC50 600000±n/a nM
Citation Flaten GEKottra GStensen WIsaksen GKarstad RSvendsen JSDaniel HSvenson J In vitro characterization of human peptide transporter hPEPT1 interactions and passive permeation studies of short cationic antimicrobial peptides. J Med Chem 54:2422-32 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Oligopeptide transporter small intestine isoform
Name:Oligopeptide transporter small intestine isoform
Synonyms:Intestinal H(+)/peptide cotransporter | Oligopeptide transporter, small intestine isoform | Peptide transporter 1
Type:PROTEIN
Mol. Mass.:78818.07
Organism:Homo sapiens (Human)
Description:ChEMBL_1488839
Residue:708
Sequence:
MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50341599
n/a
NameBDBM50341599
Synonyms:(S)-2-((S)-2-amino-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propanamido)-5-guanidinopentanamide | (S)-2-[2-Amino-3-((S)-2,5,7-tri-tert-butyl-1H-indol-3-yl)-propionylamino]-5-guanidino-pentanoic acid amide | CHEMBL365705 | TbtR-NH2
TypeSmall organic molecule
Emp. Form.C29H49N7O2
Mol. Mass.527.7451
SMILESCC(C)(C)c1[nH]c2c(cc(cc2c1C[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(C)(C)C)C(C)(C)C |r|
Structure
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