| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 7 |
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| Ligand | BDBM50341854 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_743703 (CHEMBL1767472) |
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| IC50 | 29700±n/a nM |
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| Citation |  Botta, CB; Cabri, W; Cini, E; De Cesare, L; Fattorusso, C; Giannini, G; Persico, M; Petrella, A; Rondinelli, F; Rodriquez, M; Russo, A; Taddei, M Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation. J Med Chem54:2165-82 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 7 |
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| Name: | Histone deacetylase 7 |
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| Synonyms: | HD7 | HDAC7 | HDAC7A | HDAC7_HUMAN | Histone acetylase 7 (HDAC7) | Histone deacetylase 7A | Human HDAC7 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 102942.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WUI4 |
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| Residue: | 952 |
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| Sequence: | MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVG
PQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPL
ETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKE
SAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSV
APFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGG
TLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEP
LPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVV
DDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRP
LSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSR
HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD
NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNG
FAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQ
DPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRI
VVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALE
GGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQR
LASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
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| BDBM50341854 |
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| n/a |
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| Name | BDBM50341854 |
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| Synonyms: | CHEMBL1767039 | N9-(3-(6-Chloropyridin-3-yl)phenyl)-2-(hydroxyimino)-N1-methylnonanediamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25ClN4O3 |
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| Mol. Mass. | 416.901 |
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| SMILES | CNC(=O)C(CCCCCCC(=O)Nc1cccc(c1)-c1ccc(Cl)nc1)N=O |
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| Structure | 
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