| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 4 |
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| Ligand | BDBM50341880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_743286 (CHEMBL1767485) |
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| EC50 | 23±n/a nM |
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| Citation |  El-Tayeb, A; Qi, A; Nicholas, RA; Müller, CE Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J Med Chem54:2878-90 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 4 |
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| Name: | P2Y purinoceptor 4 |
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| Synonyms: | NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40977.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_751027 |
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| Residue: | 365 |
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| Sequence: | MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
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| BDBM50341880 |
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| n/a |
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| Name | BDBM50341880 |
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| Synonyms: | ((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate | CHEMBL1767409 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15N2O14P3S |
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| Mol. Mass. | 500.207 |
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| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=S)[nH]c1=O |r| |
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| Structure | 
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