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TargetP2Y purinoceptor 4
LigandBDBM50118213
Substrate/Competitorn/a
Meas. Tech.ChEMBL_743276 (CHEMBL1767475)
EC50 88±n/a nM
Citation El-Tayeb, AQi, ANicholas, RAMüller, CE Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J Med Chem54:2878-90 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2Y purinoceptor 4
Name:P2Y purinoceptor 4
Synonyms:NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:PROTEIN
Mol. Mass.:40977.17
Organism:Homo sapiens (Human)
Description:ChEMBL_751027
Residue:365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
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  Blast E-value cutoff:
BDBM50118213
n/a
NameBDBM50118213
Synonyms:5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(tetrahydrogen triphosphate) | uridine 5'-triphosphoric acid
TypeSmall organic molecule
Emp. Form.C9H15N2O15P3
Mol. Mass.484.1411
SMILESO[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure
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