| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50341920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_743423 (CHEMBL1767777) |
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| IC50 | 930±n/a nM |
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| Citation |  Manley, PJ; Zartman, A; Paone, DV; Burgey, CS; Henze, DA; Della Penna, K; Desai, R; Leitl, MD; Lemaire, W; White, RB; Yeh, S; Urban, MO; Kane, SA; Hartman, GD; Bilodeau, MT; Trotter, BW Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia. Bioorg Med Chem Lett21:2359-64 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50341920 |
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| n/a |
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| Name | BDBM50341920 |
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| Synonyms: | ((4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)(2-(pyridin-4-yl)thiazol-4-yl)methanone | ((4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)(pyridin-2-yl)methanone | (3-(2-fluorophenyl)-1H-pyrazol-5-yl)((4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)methanone | CHEMBL1765092 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N3O2S |
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| Mol. Mass. | 419.539 |
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| SMILES | OC1(CCN([C@H]2CCCC[C@@H]12)C(=O)c1csc(n1)-c1ccncc1)c1ccccc1 |r| |
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| Structure | 
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