| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 2 |
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| Ligand | BDBM50106497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_743507 (CHEMBL1767948) |
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| Ki | 95±n/a nM |
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| Citation |  Vintonyak, VV; Waldmann, H; Rauh, D Using small molecules to target protein phosphatases. Bioorg Med Chem19:2145-55 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 2 |
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| Name: | M-phase inducer phosphatase 2 |
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| Synonyms: | CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 64985.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 580 |
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| Sequence: | MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
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| BDBM50106497 |
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| n/a |
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| Name | BDBM50106497 |
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| Synonyms: | 6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline-5,8-dione | 6-chloro-7-(2-morpholinoethylamino)quinoline-5,8-dione | CHEMBL337173 | NSC-663284 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16ClN3O3 |
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| Mol. Mass. | 321.759 |
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| SMILES | Oc1c(Cl)c(N=CCN2CCOCC2)c(O)c2ncccc12 |w:6.6| |
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| Structure | 
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