| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50342719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_744202 (CHEMBL1771959) |
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| Ki | 0.25±n/a nM |
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| Citation |  Ortega, R; Hübner, H; Gmeiner, P; Masaguer, CF Aromatic ring functionalization of benzolactam derivatives: new potent dopamine D3 receptor ligands. Bioorg Med Chem Lett21:2670-4 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50342719 |
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| n/a |
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| Name | BDBM50342719 |
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| Synonyms: | 2,4-dimethyl-5-(4-methyl-5-(3-(5-(4-(trifluoromethyl)phenyl)-2-azabicyclo[3.1.0]hexan-2-yl)propylthio)-4H-1,2,4-triazol-3-yl)thiazole | CHEMBL1771253 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26F3N5S2 |
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| Mol. Mass. | 493.611 |
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| SMILES | Cc1nc(C)c(s1)-c1nnc(SCCCN2CCC3(CC23)c2ccc(cc2)C(F)(F)F)n1C |
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| Structure | 
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