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TargetMelatonin receptor type 1B
LigandBDBM50260394
Substrate/Competitorn/a
Meas. Tech.ChEMBL_744408 (CHEMBL1772362)
IC50 4000±n/a nM
Citation Leclerc, VEttaoussi, MRami, MFarce, ABoutin, JADelagrange, PCaignard, DHRenard, PBerthelot, PYous, S Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3. Eur J Med Chem46:1622-9 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor type 1B
Name:Melatonin receptor type 1B
Synonyms:MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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BDBM50260394
n/a
NameBDBM50260394
Synonyms:5-MCA-NAT | 5-methoxycarbonylamino-N-acetyltryptamine | CHEMBL504585 | methyl 3-(2-acetamidoethyl)-1H-indol-5-ylcarbamate
TypeSmall organic molecule
Emp. Form.C14H17N3O3
Mol. Mass.275.3031
SMILESCOC(=O)Nc1ccc2[nH]cc(CCNC(C)=O)c2c1
Structure
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