Reaction Details |
| Report a problem with these data |
Target | Melatonin receptor type 1B |
---|
Ligand | BDBM50260394 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_744408 (CHEMBL1772362) |
---|
IC50 | 4000±n/a nM |
---|
Citation | Leclerc, V; Ettaoussi, M; Rami, M; Farce, A; Boutin, JA; Delagrange, P; Caignard, DH; Renard, P; Berthelot, P; Yous, S Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3. Eur J Med Chem46:1622-9 (2011) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Melatonin receptor type 1B |
---|
Name: | Melatonin receptor type 1B |
Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
Type: | Enzyme |
Mol. Mass.: | 40203.54 |
Organism: | Homo sapiens (Human) |
Description: | P49286 |
Residue: | 362 |
Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
|
|
|
BDBM50260394 |
---|
n/a |
---|
Name | BDBM50260394 |
Synonyms: | 5-MCA-NAT | 5-methoxycarbonylamino-N-acetyltryptamine | CHEMBL504585 | methyl 3-(2-acetamidoethyl)-1H-indol-5-ylcarbamate |
Type | Small organic molecule |
Emp. Form. | C14H17N3O3 |
Mol. Mass. | 275.3031 |
SMILES | COC(=O)Nc1ccc2[nH]cc(CCNC(C)=O)c2c1 |
Structure |
|