| Reaction Details |
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 | Report a problem with these data |
| Target | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Ligand | BDBM50342775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_744409 (CHEMBL1772363) |
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| IC50 | 9.1±n/a nM |
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| Citation |  Leclerc, V; Ettaoussi, M; Rami, M; Farce, A; Boutin, JA; Delagrange, P; Caignard, DH; Renard, P; Berthelot, P; Yous, S Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3. Eur J Med Chem46:1622-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Synonyms: | Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Type: | Protein |
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| Mol. Mass.: | 25917.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16083 |
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| Residue: | 231 |
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| Sequence: | MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
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| BDBM50342775 |
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| n/a |
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| Name | BDBM50342775 |
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| Synonyms: | CHEMBL457992 | N-(2-(7-(N-methylsulfamoyl)naphthalen-1-yl)ethyl)furan-2-carboxamide | N-[2-(7-methylsulfamoyl-naphth-1-yl)ethyl]furan-2-ylcarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N2O4S |
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| Mol. Mass. | 358.412 |
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| SMILES | CNS(=O)(=O)c1ccc2cccc(CCNC(=O)c3ccco3)c2c1 |
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| Structure | 
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