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TargetKappa-type opioid receptor
LigandBDBM50343251
Substrate/Competitorn/a
Meas. Tech.ChEMBL_745571 (CHEMBL1775888)
Ki>8000±n/a nM
Citation Lozama, ACunningham, CWCaspers, MJDouglas, JTDersch, CMRothman, RBPrisinzano, TE Opioid receptor probes derived from cycloaddition of the hallucinogen natural product salvinorin A. J Nat Prod74:718-26 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kappa-type opioid receptor
Name:Kappa-type opioid receptor
Synonyms:K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42648.76
Organism:Homo sapiens (Human)
Description:P41145
Residue:380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50343251
n/a
NameBDBM50343251
Synonyms:(2S,4aR,6aR,7R,9S,10aS,10bR)-Methyl 9-acetoxy-6a,10bdimethyl-2-(naphthalen-2-yl)-4,10-dioxododecahydro-1Hbenzo[f]isochromene-7-carboxylate | CHEMBL1773754
TypeSmall organic molecule
Emp. Form.C29H32O7
Mol. Mass.492.5602
SMILESCOC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccc2ccccc2c1 |r|
Structure
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