| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent GABA transporter 2 |
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| Ligand | BDBM24183 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_745625 (CHEMBL1775995) |
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| IC50 | 27542±n/a nM |
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| Citation |  Hack, S; Wörlein, B; Höfner, G; Pabel, J; Wanner, KT Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors. Eur J Med Chem46:1483-98 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium- and chloride-dependent GABA transporter 2 |
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| Name: | Sodium- and chloride-dependent GABA transporter 2 |
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| Synonyms: | GABA transporter | GABA transporter 3 | Gabt2 | Gabt3 | Gat-3 | Gat2 | Gat3 | S6A13_MOUSE | Slc6a13 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68283.40 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1460089 |
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| Residue: | 602 |
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| Sequence: | MENRASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPY
LCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQM
IVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTSENAT
SPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATF
PYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTAL
GSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFI
AYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLI
LIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNI
EDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALS
SMICIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKNQPEPTAPATPMTSLLRLTELES
NC
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| BDBM24183 |
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| n/a |
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| Name | BDBM24183 |
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| Synonyms: | 4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic acid | Aminalon | CHEMBL96 | GABA | Gamma-Aminobutyric acid | [3H]GABA | cid_119 |
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| Type | Radiolabeled ligand |
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| Emp. Form. | C4H9NO2 |
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| Mol. Mass. | 103.1198 |
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| SMILES | NCCCC(O)=O |
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| Structure | 
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