| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50343622 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_746382 (CHEMBL1776341) |
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| Ki | 0.91±n/a nM |
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| Citation |  Li, ZJ; Ren, HY; Cui, MC; Deuther-Conrad, W; Tang, RK; Steinbach, J; Brust, P; Liu, BL; Jia, HM Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging. Bioorg Med Chem19:2911-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50343622 |
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| n/a |
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| Name | BDBM50343622 |
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| Synonyms: | 1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-methylbenzyl)-piperazine | CHEMBL1774732 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O2 |
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| Mol. Mass. | 324.4168 |
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| SMILES | Cc1ccc(CN2CCN(Cc3ccc4OCOc4c3)CC2)cc1 |
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| Structure | 
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