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TargetDelta-type opioid receptor
LigandBDBM50343626
Substrate/Competitorn/a
Meas. Tech.ChEMBL_746789 (CHEMBL1777019)
Ki 39±n/a nM
Citation Zhang, BZhang, TSromek, AWScrimale, TBidlack, JMNeumeyer, JL Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors. Bioorg Med Chem19:2808-16 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50343626
n/a
NameBDBM50343626
Synonyms:(5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphinan-3-yl-((-)-14-methoxyl-17-N-cyclobutylmethyl)morphinan-3-yl-decanedioate | CHEMBL1774948
TypeSmall organic molecule
Emp. Form.C51H66N2O8
Mol. Mass.835.0783
SMILESCO[C@@]12CCCC[C@@]11CCN(CC3CCC3)[C@@H]2Cc2ccc(OC(=O)CCCCCCCCC(=O)Oc3ccc4C[C@H]5N(CC=C)CC[C@@]67[C@@H](Oc3c46)C(=O)CC[C@@]57O)cc12 |r,TLB:11:10:18.60.17:2|
Structure
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