| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-3 |
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| Ligand | BDBM50343689 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_745978 (CHEMBL1775277) |
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| IC50 | 350000±n/a nM |
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| Citation |  Albohy, A; Mohan, S; Zheng, RB; Pinto, BM; Cairo, CW Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes. Bioorg Med Chem19:2817-22 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-3 |
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| Name: | Sialidase-3 |
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| Synonyms: | NEU3 | NEUR3_HUMAN | Sialidase 3 | Sialidase-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48257.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_461856 |
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| Residue: | 428 |
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| Sequence: | MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRR
GLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSG
RNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYT
YYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVL
YCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSS
KDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRP
WILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGR
NPSQFKSN
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| BDBM50343689 |
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| n/a |
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| Name | BDBM50343689 |
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| Synonyms: | (3S,4R,5R)-4-acetamido-3-(4-((8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl)-1H-1,2,3-triazol-1-yl)-5-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid | CHEMBL1773348 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H46N4O6 |
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| Mol. Mass. | 606.7522 |
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| SMILES | CCC(CC)O[C@@H]1CC(=C[C@@H]([C@H]1NC(C)=O)n1cc(nn1)[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C)C(O)=O |r,c:8| |
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| Structure | 
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