| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50343856 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_747359 (CHEMBL1776704) |
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| IC50 | 2900±n/a nM |
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| Citation |  Zhu, L; Jin, J; Liu, C; Zhang, C; Sun, Y; Guo, Y; Fu, D; Chen, X; Xu, B Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors. Bioorg Med Chem19:2797-807 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50343856 |
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| n/a |
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| Name | BDBM50343856 |
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| Synonyms: | 4-(2-(3-(3,4-Dichlorophenyl)ureido)-6-nitroquinazolin-4-ylamino)benzoic acid | CHEMBL1774790 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H14Cl2N6O5 |
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| Mol. Mass. | 513.29 |
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| SMILES | OC(=O)c1ccc(Nc2nc(NC(=O)Nc3ccc(Cl)c(Cl)c3)nc3ccc(cc23)[N+]([O-])=O)cc1 |
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| Structure | 
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