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TargetAtrial natriuretic factor
LigandBDBM50085452
Substrate/Competitorn/a
Meas. Tech.ChEMBL_748204
IC50 3.4±n/a nM
Citation Glossop MSBazin RJDack KNFox DNMacDonald GAMills MOwen DRPhillips CReeves KARinger TJStrang RSWatson CA Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors. Bioorg Med Chem Lett 21:3404-6 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Atrial natriuretic factor
Name:Atrial natriuretic factor
Synonyms:ANF | ANP | Atrial natriuretic peptide | CDD-ANF | CDP | Cardiodilatin-related peptide | Natriuretic peptides A | Prepronatriodilatin
Type:PROTEIN
Mol. Mass.:16708.32
Organism:Homo sapiens (Human)
Description:ChEMBL_748204
Residue:153
Sequence:
MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPP
QVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLT
APRSLRRSSCFGGRMDRIGAQSGLGCNSFRYRR
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  Blast E-value cutoff:
BDBM50085452
n/a
NameBDBM50085452
Synonyms:(S)-2-[((S)-6-Amino-2-methanesulfonylamino-hexanoylamino)-methyl]-3-{1-[(S)-1-carboxy-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-cyclopentyl}-propionic acid | CHEMBL42583 | Sampatrilat
TypeSmall organic molecule
Emp. Form.C26H40N4O9S
Mol. Mass.584.682
SMILESCS(=O)(=O)N[C@@H](CCCCN)C(=O)NC[C@H](CC1(CCCC1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(O)=O
Structure
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