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TargetAtrial natriuretic factor
LigandBDBM50344188
Substrate/Competitorn/a
Meas. Tech.ChEMBL_748204
IC50 130±n/a nM
Citation Glossop MSBazin RJDack KNFox DNMacDonald GAMills MOwen DRPhillips CReeves KARinger TJStrang RSWatson CA Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors. Bioorg Med Chem Lett 21:3404-6 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Atrial natriuretic factor
Name:Atrial natriuretic factor
Synonyms:ANF | ANP | Atrial natriuretic peptide | CDD-ANF | CDP | Cardiodilatin-related peptide | Natriuretic peptides A | Prepronatriodilatin
Type:PROTEIN
Mol. Mass.:16708.32
Organism:Homo sapiens (Human)
Description:ChEMBL_748204
Residue:153
Sequence:
MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPP
QVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLT
APRSLRRSSCFGGRMDRIGAQSGLGCNSFRYRR
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  Blast E-value cutoff:
BDBM50344188
n/a
NameBDBM50344188
Synonyms:(S)-2-(1-((S)-1-carboxy-2-(4-ethyloxazol-2-yl)ethylcarbamoyl)cyclopentylamino)pentanoic acid | CHEMBL1778527
TypeSmall organic molecule
Emp. Form.C19H29N3O6
Mol. Mass.395.4501
SMILESCCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(CC)co1)C(O)=O)C(O)=O |r|
Structure
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