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TargetAtrial natriuretic factor
LigandBDBM50344197
Substrate/Competitorn/a
Meas. Tech.ChEMBL_748204
IC50 58±n/a nM
Citation Glossop MSBazin RJDack KNFox DNMacDonald GAMills MOwen DRPhillips CReeves KARinger TJStrang RSWatson CA Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors. Bioorg Med Chem Lett 21:3404-6 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Atrial natriuretic factor
Name:Atrial natriuretic factor
Synonyms:ANF | ANP | Atrial natriuretic peptide | CDD-ANF | CDP | Cardiodilatin-related peptide | Natriuretic peptides A | Prepronatriodilatin
Type:PROTEIN
Mol. Mass.:16708.32
Organism:Homo sapiens (Human)
Description:ChEMBL_748204
Residue:153
Sequence:
MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPP
QVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLT
APRSLRRSSCFGGRMDRIGAQSGLGCNSFRYRR
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  Blast E-value cutoff:
BDBM50344197
n/a
NameBDBM50344197
Synonyms:(S)-2-(1-((S)-1-carboxy-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethylcarbamoyl)cyclopentylamino)-4-methoxybutanoic acid | CHEMBL1778536
TypeSmall organic molecule
Emp. Form.C22H28N4O7
Mol. Mass.460.4803
SMILESCOCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(no1)-c1ccccc1)C(O)=O)C(O)=O |r|
Structure
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