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TargetNatriuretic peptides A
LigandBDBM50344197
Substrate/Competitorn/a
Meas. Tech.ChEMBL_748204 (CHEMBL1780285)
IC50 58±n/a nM
Citation Glossop, MSBazin, RJDack, KNFox, DNMacDonald, GAMills, MOwen, DRPhillips, CReeves, KARinger, TJStrang, RSWatson, CA Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors. Bioorg Med Chem Lett21:3404-6 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Natriuretic peptides A
Name:Natriuretic peptides A
Synonyms:ANF | ANF_HUMAN | ANP | Atrial natriuretic factor | Atrial natriuretic peptide | CDD-ANF | CDP | Cardiodilatin-related peptide | NPPA | Natriuretic peptides A | PND | Prepronatriodilatin
Type:PROTEIN
Mol. Mass.:16393.93
Organism:Homo sapiens (Human)
Description:ChEMBL_748204
Residue:151
Sequence:
MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPP
QVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLT
APRSLRRSSCFGGRMDRIGAQSGLGCNSFRY
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  Blast E-value cutoff:
BDBM50344197
n/a
NameBDBM50344197
Synonyms:(S)-2-(1-((S)-1-carboxy-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethylcarbamoyl)cyclopentylamino)-4-methoxybutanoic acid | CHEMBL1778536
TypeSmall organic molecule
Emp. Form.C22H28N4O7
Mol. Mass.460.4803
SMILESCOCC[C@H](NC1(CCCC1)C(=O)N[C@@H](Cc1nc(no1)-c1ccccc1)C(O)=O)C(O)=O |r|
Structure
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