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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sigma non-opioid intracellular receptor 1 | ||
| Ligand | BDBM50344432 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_748646 (CHEMBL1780499) | ||
| Ki | 174±n/a nM | ||
| Citation |  Rack, E; Fröhlich, R; Schepmann, D; Wünsch, B Design, synthesis and pharmacological evaluation of spirocyclics(1) receptor ligands with exocyclic amino moiety (increased distance 1). Bioorg Med Chem19:3141-51 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sigma non-opioid intracellular receptor 1 | |||
| Name: | Sigma non-opioid intracellular receptor 1 | ||
| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein | ||
| Type: | Protein | ||
| Mol. Mass.: | 25307.17 | ||
| Organism: | Cavia porcellus (Guinea pig) | ||
| Description: | Q60492 | ||
| Residue: | 223 | ||
| Sequence: |
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| BDBM50344432 | |||
| n/a | |||
| Name | BDBM50344432 | ||
| Synonyms: | CHEMBL1779996 | cis-N-(p-Methoxybenzyl)-3-methoxy-3,4-dihydrospiro-[[2]benzopyran-1,1'-cyclohexan]-4'-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H29NO3 | ||
| Mol. Mass. | 367.4813 | ||
| SMILES | COC1Cc2ccccc2[C@]2(CC[C@@H](CC2)NCc2ccc(OC)cc2)O1 |r,wU:13.17,10.28,(14.88,-7.34,;13.54,-8.1,;13.54,-9.64,;14.87,-10.42,;14.86,-11.96,;16.17,-12.71,;16.17,-14.23,;14.85,-15.01,;13.53,-14.23,;13.54,-12.71,;12.2,-11.95,;10.93,-12.36,;9.3,-11.74,;8.53,-13.09,;9.72,-12.67,;11.43,-13.29,;7.2,-12.33,;7.2,-10.78,;5.86,-10.01,;5.86,-8.47,;4.53,-7.7,;3.19,-8.47,;1.85,-7.7,;.52,-8.48,;3.2,-10.02,;4.53,-10.79,;12.2,-10.41,)| | ||
| Structure | 
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