| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 5 member 4 |
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| Ligand | BDBM50345020 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_749157 (CHEMBL1780754) |
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| IC50 | 89.6±n/a nM |
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| Citation |  Kang, SY; Kim, MJ; Lee, JS; Lee, J Glucosides with cyclic diarylpolynoid as novel C-aryl glucoside SGLT2 inhibitors. Bioorg Med Chem Lett21:3759-63 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 5 member 4 |
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| Name: | Solute carrier family 5 member 4 |
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| Synonyms: | Low affinity sodium-glucose cotransporter | Na(+)/glucose cotransporter 3 | SAAT1 | SC5A4_HUMAN | SGLT3 | SLC5A4 | Sodium/glucose cotransporter 3 | Solute carrier family 5 member 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 72452.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_764617 |
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| Residue: | 659 |
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| Sequence: | MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFL
AGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIY
IKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLA
IFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNAT
PSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQR
CLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVG
CTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEK
ELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRV
NEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLV
TLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLK
KAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA
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| BDBM50345020 |
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| n/a |
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| Name | BDBM50345020 |
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| Synonyms: | (2R,3S,4R,5R,6S)-2-Hydroxymethyl-6-(15-oxa-tricyclo[14.2.2.0*3,8*]icosa-1(19),3(8),4,6,12,16(20),17-heptaen-5-yl)-tetrahydro-pyran-3,4,5-triol | CHEMBL1778658 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30O6 |
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| Mol. Mass. | 426.5021 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc2CCC\C=C\COc3ccc(Cc2c1)cc3 |r,t:19| |
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| Structure | 
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