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TargetP2Y purinoceptor 2
LigandBDBM50205406
Substrate/Competitorn/a
Meas. Tech.ChEMBL_751026 (CHEMBL1786811)
EC50 8±n/a nM
Citation Maruoka, HJayasekara, MPBarrett, MOFranklin, DAde Castro, SKim, NCostanzi, SHarden, TKJacobson, KA Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphated-ester modifications as selective agonists of the P2Y(4) receptor. J Med Chem54:4018-33 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2Y purinoceptor 2
Name:P2Y purinoceptor 2
Synonyms:ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:PROTEIN
Mol. Mass.:42299.21
Organism:Homo sapiens (Human)
Description:ChEMBL_1455361
Residue:377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50205406
n/a
NameBDBM50205406
Synonyms:((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate | 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate | CHEMBL373780
TypeSmall organic molecule
Emp. Form.C9H16N3O13P3S
Mol. Mass.499.222
SMILESN[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=S |r|
Structure
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