| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50345697 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_750527 (CHEMBL1786288) |
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| Ki | 5±n/a nM |
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| Citation |  Alonso, D; Vázquez-Villa, H; Gamo, AM; Martínez-Esperón, MF; Tortosa, M; Viso, A; Fernández de la Pradilla, R; Junquera, E; Aicart, E; Martín-Fontecha, M; Benhamú, B; López-Rodríguez, ML; Ortega-Gutiérrez, S Development of Fluorescent Ligands for the Human 5-HT1A Receptor. ACS Med Chem Lett1:249-253 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50345697 |
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| n/a |
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| Name | BDBM50345697 |
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| Synonyms: | 5-(Dimethylamino)-N-{7-[2-{4-[4-(1-naphthyl)piperazin-1-yl]butyl}-1,3-dioxotetrahydro-1H-pyrrolo[1,2-c]imidazol-7a(5H)-yl]heptyl}naphthalene-1-sulfonamide | CHEMBL1784933 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H56N6O4S |
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| Mol. Mass. | 753.008 |
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| SMILES | CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCCC12CCCN1C(=O)N(CCCCN1CCN(CC1)c1cccc3ccccc13)C2=O |
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| Structure | 
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