| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM35738 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_750233 (CHEMBL1788074) |
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| Ki | 5.3±n/a nM |
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| Citation |  Güzel, O; Innocenti, A; Scozzafava, A; Salman, A; Supuran, CT Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors. Bioorg Med Chem Lett19:3170-3 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM35738 |
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| n/a |
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| Name | BDBM35738 |
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| Synonyms: | sulfonamide deriv., 7f |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13BrN2O3S |
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| Mol. Mass. | 369.234 |
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| SMILES | NS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2)c(Br)c1 |
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| Structure | 
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