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TargetCarbonic anhydrase 7
LigandBDBM35730
Substrate/Competitorn/a
Meas. Tech.ChEMBL_750233
Ki 7.1±n/a nM
Citation Güzel OInnocenti AScozzafava ASalman ASupuran CT Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors. Bioorg Med Chem Lett 19:3170-3 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 7
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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  Blast E-value cutoff:
BDBM35730
n/a
NameBDBM35730
Synonyms:cid_694792 | sulfonamide deriv., 5e
TypeSmall organic molecule
Emp. Form.C13H14N2O3S2
Mol. Mass.310.392
SMILESNS(=O)(=O)c1ccc(CNC(=O)Cc2cccs2)cc1
Structure
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