| Reaction Details |
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 | Report a problem with these data |
| Target | Lysine-specific demethylase 4E |
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| Ligand | BDBM26113 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_754092 (CHEMBL1798570) |
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| Ki | 914000±n/a nM |
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| Citation |  Lohse, B; Kristensen, JL; Kristensen, LH; Agger, K; Helin, K; Gajhede, M; Clausen, RP Inhibitors of histone demethylases. Bioorg Med Chem19:3625-36 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysine-specific demethylase 4E |
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| Name: | Lysine-specific demethylase 4E |
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| Synonyms: | 2-OG-Dependent Histone Demethylase JMJD2E | Histone Lysine Demethylase | Jumonji domain-containing protein 2E (JMJD2E) | KDM4D-like protein | KDM4DL | KDM4E | KDM4E_HUMAN | Lysine-specific demethylase 4D-like | Lysine-specific demethylase 4E | Lysine-specific demethylase 4E (KDM4E) |
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| Type: | Enzyme |
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| Mol. Mass.: | 56815.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | B2RXH2 |
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| Residue: | 506 |
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| Sequence: | MKSVHSSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMY
DDIEDILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHQNFADLEQ
RYWKSHPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFG
MWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLR
HKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDY
GKMASQCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEPRVAESQELSNWRD
DIVLRRAALGLRLLPNLTAQCPTQPVSSGHCYNPKGCGTDAVPGSAFQSSAYHTQTQSLT
LGMSARVLLPSTGSWGSGRGRGRGQGQGRGCSRGRGHGCCTRELGTEEPTVQPASKRRLL
MGTRSRAQGHRPQLPLANDLMTNLSL
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| BDBM26113 |
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| n/a |
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| Name | BDBM26113 |
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| Synonyms: | 2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | pyridine-2,4-dicarboxylic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5NO4 |
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| Mol. Mass. | 167.1189 |
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| SMILES | OC(=O)c1ccnc(c1)C(O)=O |
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| Structure | 
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