| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
|---|
| Ligand | BDBM35727 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_753081 (CHEMBL1799009) |
|---|
| Ki | 437±n/a nM |
|---|
| Citation |  Biswas, S; Aggarwal, M; Güzel, Ö; Scozzafava, A; McKenna, R; Supuran, CT Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Bioorg Med Chem19:3732-8 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 13 |
|---|
| Name: | Carbonic anhydrase 13 |
|---|
| Synonyms: | CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29445.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8N1Q1 |
|---|
| Residue: | 262 |
|---|
| Sequence: | MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
FLVSNHRPPQPLKGRKVRASFH
|
|
|
|---|
| BDBM35727 |
|---|
| n/a |
|---|
| Name | BDBM35727 |
|---|
| Synonyms: | sulfonamide deriv., 5b |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H11FN2O3S2 |
|---|
| Mol. Mass. | 314.356 |
|---|
| SMILES | NS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)c(F)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
