| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM50249871 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_754274 (CHEMBL1798961) |
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| Ki | 333±n/a nM |
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| Citation |  Jagrat, M; Behera, J; Yabanoglu, S; Ercan, A; Ucar, G; Sinha, BN; Sankaran, V; Basu, A; Jayaprakash, V Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies. Bioorg Med Chem Lett21:4296-300 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
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| Type: | Protein |
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| Mol. Mass.: | 59689.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21397 |
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| Residue: | 527 |
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| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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| BDBM50249871 |
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| n/a |
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| Name | BDBM50249871 |
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| Synonyms: | 3-phenyl-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide | Amino[5-(4-methylphenyl)-3-phenyl(2-pyrazolinyl)]methane-1-thione | CHEMBL489743 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17N3S |
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| Mol. Mass. | 295.402 |
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| SMILES | Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccccc1 |c:10| |
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| Structure | 
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