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TargetLactoylglutathione lyase
LigandBDBM50027952
Substrate/Competitorn/a
Meas. Tech.ChEMBL_754309 (CHEMBL1799085)
Ki 335300±n/a nM
Citation Liu, MYuan, MLi, ZCheng, YKLuo, HBHu, X Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I. Bioorg Med Chem Lett21:4243-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lactoylglutathione lyase
Name:Lactoylglutathione lyase
Synonyms:Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase
Type:Enzyme
Mol. Mass.:20772.95
Organism:Homo sapiens (Human)
Description:Q04760
Residue:184
Sequence:
MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
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BDBM50027952
n/a
NameBDBM50027952
Synonyms:5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid | CHEMBL19490 | Zomepirac | [5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid
TypeSmall organic molecule
Emp. Form.C15H14ClNO3
Mol. Mass.291.73
SMILESCc1cc(CC(O)=O)n(C)c1C(=O)c1ccc(Cl)cc1
Structure
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