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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50274013
Substrate/Competitorn/a
Meas. Tech.ChEMBL_756374
Ki 0.300000±n/a nM
Citation Congreve MLangmead CJMason JSMarshall FH Progress in structure based drug design for G protein-coupled receptors. J Med Chem 54:4283-311 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50274013
n/a
NameBDBM50274013
Synonyms:1-(4-benzhydrylpiperazin-1-yl)-3-(3-methyl-1H-indol-4-yloxy)propan-2-ol | CHEMBL461463
TypeSmall organic molecule
Emp. Form.C29H33N3O2
Mol. Mass.455.5912
SMILESCc1c[nH]c2cccc(OCC(O)CN3CCN(CC3)C(c3ccccc3)c3ccccc3)c12
Structure
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