| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50274013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_756374 (CHEMBL1805400) |
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| Ki | 0.300000±n/a nM |
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| Citation |  Congreve, M; Langmead, CJ; Mason, JS; Marshall, FH Progress in structure based drug design for G protein-coupled receptors. J Med Chem54:4283-311 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50274013 |
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| n/a |
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| Name | BDBM50274013 |
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| Synonyms: | 1-(4-benzhydrylpiperazin-1-yl)-3-(3-methyl-1H-indol-4-yloxy)propan-2-ol | CHEMBL461463 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H33N3O2 |
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| Mol. Mass. | 455.5912 |
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| SMILES | Cc1c[nH]c2cccc(OCC(O)CN3CCN(CC3)C(c3ccccc3)c3ccccc3)c12 |
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| Structure | 
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